Application Note: Automated media exchange for spheriod cultures using a novel MultiFlo™ FX accessory
30 August 2019

Media exchanges with unattached cell models can be daunting if performed by hand, even when performed on a single plate. Multichannel pipettes must remove and dispense media at an extremely slow rate, and care must be taken to keep pipette tips away from the actual spheroids. Here, BioTek shows that through incorporation of the AMX Media Exchange Module on the MultiFlo FX, risk of accidental spheroid removal from wells is eliminated. Media is automatically removed and replaced with fresh media only, or fresh media containing treatment concentrations.