Application Note: Analysis of volatile organic compounds in drinking water with the ISQ 7610 GC-MS using HeSaver-H2 Safer technology
15 March 2024

In this application note, Thermo Fisher Scientific demonstrates a routine analytical method that meets the requirements outlined in US EPA Method 524.4 for the quantitation of volatile organic compounds (VOCs) in drinking water, using the Teledyne Tekmar Atomx XYZ Purge and Trap (P&T) system along with a Thermo Scientific™ ISQ™ 7610 MS system coupled with a Thermo Scientific™ TRACE™ 1610 gas chromatograph (GC), equipped with the Thermo Scientific™ HeSaver-H2 Safer™ technology for split/splitless (SSL) injector, and Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software. Method linearity, method detection limit (MDL), precision, and MRL were assessed to evaluate method performance. A long-term study was performed to ensure the stability of this analytical method.

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