Application Note: Evaluation of a Steroid Panel LC-MS Kit
2 April 2024

LC-MS is recommended for measuring circulating steroids, however, there is nearly no commercial solution available nor an external quality assessment scheme (EQAS) available for all clinically relevant steroids. Tecan highlights a study which aims to compare the results of the laboratory-specific procedure to Tecan's commercially available kit for the measurement of 17 circulating steroids and dexamethasone. Additionally, an evaluation of the clinical bias of the mentioned kit by using external quality control samples as a reference was performed. Since no reference measurements and/or ring trial samples are available for all steroids included in the commercial kit, the results of the serum samples are set in a clinical context afterwards.