Electrophysiological recordings of Ec-ClC activity on the SURFE²R N1

In this application note, Nanion presents Ec-ClC activity measurements on the SURFE²R N1 instrument using proteoliposomes reconstituted with purified Ec-ClC at different lipid-to-protein ratios. This assay can easily be adapted for other transporters of the ClC family and provides a useful tool in future drug discovery.