White Paper: Developing hydrophilic interaction liquid chromatography (HILIC) separation methods with HALO HILIC and HALO Penta-HILIC columns
17 July 2023
Method developers rely on reversed-phase (RP) conditions for
most of their separations. However, what happens when there are
polar analytes that are not well retained under reversed-phase
conditions? One option is to use hydrophilic interaction liquid
chromatography (HILIC). In this whitepaper, Advanced Materials Technology provides experimental data and helpful information on the development of HILIC separation methods using the HALO® HILIC and HALO® Penta-HILIC columns.