STING / TMEM173 Rabbit pAb
Product Details
- Cat. No.
- A3575
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - STING / TMEM173 antibody (A3575)
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Description
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
