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Sox11 (SRY-box containing protein 11) is a member of a family of transcription factors containing an HMG DNA-binding domain. Sox11 is important for the development of nervous system. Sox11 is upregulated in a variety of tumor types, including medulloblastomas, gliomas and epithelial ovarian tumors. In B cell lymphomas, information regarding the expression of Sox11 aids in diagnosis and prognosis. Sox11 also functions as a tumor suppressor in glioma-initiating cells.