SARS-COV-2 N Protein Rabbit mAb
Product Details
- Cat. No.
- A20021
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - SARS-COV-2 N Protein Rabbit pAb (A20021)
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Description
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: SARS-CoV-2
