Runt-related transcription factor 2 (RUNX2) is a transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. RUNX2 is essential for the maturation of osteoblasts. Defects in RUNX2 are the cause of cleidocranial dysplasia (CLCD), also known as cleidocranial dysostosis (CCD). CLCD is an autosomal dominant skeletal disorder with high penetrance and variable expressivity.
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RUNX2.
- Isotype: Rabbit Ig
- Gene: Q13950
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)
