Pokemon (POK erythroid myeloid ontogenic factor) plays a key role in the instruction of early lymphoid progenitors to develop into B lineage cells by repressing T-cell instructive Notch signals. Pokemon specifically represses the transcription of the CDKN2A gene, and efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Pokemon binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term of human Pokemon.
- Isotype: Rabbit Ig
- Gene: O95365
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)
