Paired box protein Pax-8 (Pax-8) is a transcription factor involved in thyroid-specific gene expression, maintaining the functional differentiation of such cells. Defects in Pax-8 are the cause of congenital hypothyroidism non-goitrous type 2 (CHNG2). CHNG2 is a disease characterized by thyroid dysgenesis, the most frequent cause of congenital hypothyroidism, accounting for 85% of cases.
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Dog (Canine), Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Pax-8.
- Isotype: Rabbit Ig
- Gene: Q06710
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
- ELISA (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)
