Cyclin-dependent kinase inhibitor 2A (CDKN2A or p16-INK4a) acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclin D and to phosphorylate the retinoblastoma protein.
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Recombinant human p16-INK4a.
- Clone: IMD-16
- Isotype: Mouse IgG1
- Gene: P51480
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
- ELISA (ELISA)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)
