Product & ReviewsAntibodies

Lipin 1 Rabbit mAb

Product Details

Cat. No.
A3326
Type
Primary Antibody
Clonality
Monoclonal
Host
Rabbit
ABclonal Technology

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Description

This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017]

Biological Information

  • Clonality: Monoclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rat

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