Product & ReviewsAntibodies
LIG1 Rabbit pAb
Product Details
- Cat. No.
- A1858
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit

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Description
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse