Product & ReviewsAntibodies
CyFlow™ Perforin PE
Product Details
- Cat. No.
- AC676621
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Perforin is a 70 kDa cytolytic protein with structural and functional similarities to complement component 9 (C9). It is stored in cytoplasmic granules of cytotoxic T cells and NK cells and after its release it forms transmembrane pores in the target cells to kill it. As perforin is a key effector molecule for cell-mediated cytolysis, defects of its gene can cause severe disorders.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Cow, Human
- Antigen: Perforin
- Clone: dG9
- Conjugate: PE
- Isotype: IgG2b
Handling
- Quantity: 100 tests
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
Applications
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)