Product & ReviewsAntibodies
CyFlow™ CD86 Low Endotoxin
Product Details
- Cat. No.
- BF446321
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
CD86 (B7-2) and CD80 (B7-1) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CD152 (CTLA-4). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Antigen: CD86
- Clone: GL-1
- Conjugate: Low Endotoxin
- Isotype: IgG2a
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
Applications
- Flow Cytometry (FC)
- Functional Studies (Func)
- Immunocytochemistry (ICC)
- Immunohistochemistry (Formalin-Fixed Sections) (IHC (F))
- Immunoprecipitation (IP)