CyFlow™ CD62P Purified
Product Details
- Cat. No.
- AR454696
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Non-Human Primate
- Antigen: CD62P
- Clone: AK4
- Conjugate: Purified
- Isotype: IgG1
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
Applications
- Flow Cytometry (FC)
- Functional Studies (Func)
- Immunocytochemistry (ICC)
- Immunoprecipitation (IP)
- Western Blotting (WB)