CyFlow™ CD58 Biotin
Product Details
- Cat. No.
- CE076390
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form; the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Pig (Swine)
- Antigen: CD58
- Clone: MEM-63
- Conjugate: Biotin
- Isotype: IgG1
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in Tris buffered saline (TBS) solution, pH ≈8.0, containing 0.1% (w/v) sodium azide.
Applications
- Flow Cytometry (FC)