Product & ReviewsAntibodies
CyFlow™ CD42b Purified
Product Details
- Cat. No.
- AB107492
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD42b (GPIb α) composes together with GPIb β, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD42b
- Clone: AK2
- Conjugate: Purified
- Isotype: IgG1
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
Applications
- ELISA (ELISA)
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)
- Immunoprecipitation (IP)
- Western Blotting (WB)