Product & ReviewsAntibodies

CyFlow™ CD300e Purified

Product Details

Cat. No.
BT723227
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Sysmex Europe SE

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Description

CD300e (IREM-2; immune receptor expressed by myeloid cells 2, CLM2 or LMIR6) is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD300e
  • Clone: UP-H2
  • Conjugate: Purified
  • Isotype: IgG1

Handling

  • Quantity: 0.1 mg
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

  • Flow Cytometry (FC)
  • Functional Studies (Func)
  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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