Product & ReviewsAntibodies
CyFlow™ CD195 Purified
Product Details
- Cat. No.
- AQ470181
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD195 (CCR5, CKR-5) is a receptor for inflammatory CC-chemokines (characterized by a pair of adjacent cysteine residues), such as MIP-1 α, MIP-1 β, or RANTES. It is a G protein-associated seven-pass transmembrane protein expressed on resting T cells with memory/effector phenotype, monocytes, macrophages and immature dendritic cells. This chemokine receptor regulates the activation and directed migration of leukocytes. Importantly, along with CD4, CD195 functions as a major receptor for HIV. Their ligand is the viral glycoprotein gp120.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD195
- Clone: T21/8
- Conjugate: Purified
- Isotype: IgG1
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
Applications
- ELISA (ELISA)
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)
- Immunoprecipitation (IP)
- Western Blotting (WB)