Product & ReviewsAntibodies
CyFlow™ CD178 Low Endotoxin
Product Details
- Cat. No.
- BG866777
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD178 (Fas-L; Fas ligand or CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor Fas/CD95. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE). CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD178
- Clone: NOK-1
- Conjugate: Low Endotoxin
- Isotype: IgG1
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
Applications
- Flow Cytometry (FC)
- Functional Studies (Func)
- Immunocytochemistry (ICC)
- Immunoprecipitation (IP)
- Western Blotting (WB)