CyFlow™ CD160 Purified
Product Details
- Cat. No.
- CT688691
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD160
- Clone: BY55
- Conjugate: Purified
- Isotype: IgM
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in Tris buffered saline (TBS) solution, pH ≈8.0, containing 0.1% (w/v) sodium azide.
Applications
- Flow Cytometry (FC)
- Immunoprecipitation (IP)