Product & ReviewsAntibodies
CyFlow™ ABRA1 Purified
Product Details
- Cat. No.
- AP667270
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
ABRA1 (Abraxas, CCDC98) is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: ABRA1
- Clone: ABRA1-01
- Conjugate: Purified
- Isotype: IgG
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
Applications
- Flow Cytometry (FC)
- Immunoprecipitation (IP)
- Western Blotting (WB)