STAT1, also known as signal transduction and activator of transcription 1, is a ubiquitously expressed cytoplasmic protein and is activated in response to cytokine signaling, including IFN-α, IFN-γ, EGF, PDGF, and IL-6. Upon activation, STAT1 is phosphorylated by receptor-associated kinases, translocates to the nucleus, and functions as a transcription factor.
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Cytoplasm; phosphorylated form translocated to the nucleus.
- Clone: 10C4B40
- Conjugate: Purified
- Isotype: IgG1 κ
- Quantity: 100 µg
- Storage: This Purified conjugate is stable when stored at 2-8°C. Do not freeze.