Product & ReviewsAntibodies
Anti-Rat MAG (Clone 118423)
Product Details
- Cat. No.
- M1279
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Myelin-associated glycoprotein (MAG) is a transmembrane proteins that is a component of myelin in the central and peripheral nervous system.1 It promotes neurite outgrowth during the embryonic development, but inhibits axonal regeneration in the adult nervous system.2 MAG mediates cell-cell interactions between myelinating glial cells and neurons.3 MAG as an important component of the myelin-derived inhibition of nerve regeneration. The acute loss of MAG function can promote significant axon growth across a site of CNS nerve damage.4
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Rat
- Clone: 118423
- Conjugate: Purified No Carrier Protein
- Isotype: IgG2a
- Gene: 29409
Handling
- Quantity: 25 µg, 500 µg
- Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Applications
- ELISA (ELISA)
- In Situ Hybridization (ISH)
- Mass Cytometry (CyTOF)