Excellent marker for wild-type and mutant forms of human p53 antigen. Epitope recognized by Bp53.11: 20-SDLWKLLPENNV-31. The antibody stains positively approx. 60 % of investigated carcinoma of lung, breast, colon, stomach, esophagus, pancreas, urinary bladder and testis, head and neck tumors; T-cell Leukemia, non-Hodgkin-Lymphoma, melanoma, sarcoma
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Recombinant human p53 (transcription domain within the NH2 terminus)
- Clone: Bp53.11
- Conjugate: unconjugated
- Isotype: IgG2a
- Quantity: 1 mL (25 µg/mL)
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- ELISA (ELISA)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)