EP-4 recognizes the HLA-B27 cell surface antigen on human cells. HLA-B27 has been found to be highly associated (60%) with ankylosing spondylitis (Bekhterev's disease, Marie-Strümpell disease or "bamboo spine"). While rheumatoid factor tests will be negative, testing for the presence of HLA-B27 in a patient can confirm the diagnosis of ankylosing spondylitis. Also postgonococcal arthritis and acute anterior uveitis are associated with HLA-B27
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: lymphocytes from an HLA-B27 patient
- Clone: EP-4
- Conjugate: unconjugated
- Isotype: IgM kappa
- Quantity: 1 mL (100 µg/ml)
- Storage: store at 2-8°C
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)