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Anti-IL2RA monoclonal antibody, clone MEM-181 [R-PE]

Creative Diagnostics
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Product Details

Cat. No.
CABT-48019MH
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Creative Diagnostics

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Product Overview

Anti-IL2RA monoclonal antibody, clone MEM-181 [R-PE]

Creative Diagnostics
0.0/5.0
|0 Reviews

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Creative Diagnostics

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  • Summary
  • Reviews

Description

Mouse Anti-Human IL2RA monoclonal antibody for FC. Mouse anti Human CD25, clone MEM-181 recognizes the 55kD alpha subunit of the human IL-2 receptor, also known as p55 or TAC antigen, CD25 is a type 1 transmembrane protein with two Sushi domains, also known as short concensus repeats (SCRs) or complement control protein (CCP) modules located within its extracellular domain. The IL-2 receptor exists in three forms. A high affinity form consiting of a non-covalently linked heterodimer composed of the alpha subunit (CD25) and the IL-2 receptor beta subunit also known as CD122 or p75, a medium affinity beta subunit (CD122) monomer or a low affinity alpha (CD25) subunit monomer. CD25 is expressed by activated T lymphocytes and activated B lymphocytes responding to antigen or mitogen stimulation. CD25 is also expressed in some thymocytes and oligodendrocytes. In disease, elevated expression of CD25 in noted in a number of chronic inflammatory conditions, tuberculoid leprosy patients demonstrate markedly elevated levels of circulating CD25high FoxP3+ regulatory T cells (T-regs). Elevated levels of CD25 antigen expression are often seen in cases of non-Hodgkin s lymphoma and diffuse large B cell lymphoma. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Conjugate: R-PE
  • Isotype: IgG1
  • Gene: 3559

Handling

  • Quantity: 100 Tests
  • Storage: Prior to reconstitution store at +4°C. Following reconstitution store at +4°C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
Specificity rating
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