Product & ReviewsAntibodies
Anti-Human TRAIL R2
Product Details
- Cat. No.
- T451- 500 µg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.1 The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.2 TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients.3
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: 71903
- Conjugate: Purified No Carrier Protein
- Isotype: IgG1
- Gene: 8795
Handling
- Quantity: 500 µg
- Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Applications
- Blocking (BA)
- Western Blotting (WB)