Product & ReviewsAntibodies
Anti-Human SMAC
Product Details
- Cat. No.
- S585-100 µg
- Clonality
- Polyclonal
- Host
- Rat
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
Second Mitochondria Derived Activator of Caspase (SMAC) is a mitochondrial apoptogenic protein that is released to the cytosol in response to diverse apoptotic stimuli, including commonly used chemotherapeutic drugs.1 SMAC promotes cytochrome-c dependent activation by eliminating the inhibition of IAP - a protein that negatively regulates apoptosis or programmed cell death.2
Biological Information
- Clonality: Polyclonal
- Host: Rat
- Reactivity: Human
- Conjugate: Antigen Affinity Purified
- Gene: 56616
Handling
- Quantity: 100 µg
- Storage: The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Applications
- Western Blotting (WB)