Product & ReviewsAntibodies
Anti-Human IFN-γ Rα Chain (CD119)
Product Details
- Cat. No.
- I-691-25 µg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
- Clone: 92101
- Conjugate: Purified No Carrier Protein
- Isotype: IgG1
- Gene: 3459
Handling
- Quantity: 25 µg
- Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Applications
- Neutralization (Neut)
- Western Blotting (WB)