Product & ReviewsAntibodies
Anti-Human IFN-γ
Product Details
- Cat. No.
- I-646
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: 25718
- Conjugate: Purified No Carrier Protein
- Isotype: IgG2a
Handling
- Quantity: 100 µg, 25 µg, 500 µg
- Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- In Situ Hybridization (ISH)
- Neutralization (Neut)
- Western Blotting (WB)