Product & ReviewsAntibodies

Anti-Human BMP-6

Product Details

Cat. No.
B578- 25 µg
Clonality
Polyclonal
Host
Goat
Leinco Technologies

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Description

Bone morphogenetic protein 6, also known as BMP6, is a human gene. The protein encoded by this gene is a a member of the TGFβ superfamily. Bone morphogenetic proteins are known for their ability to induce the growth of bone and cartilage. BMP6 is able to induce all osteogenic markers in mesenchymal stem cells. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.

Biological Information

  • Clonality: Polyclonal
  • Host: Goat
  • Reactivity: Human
  • Conjugate: Antigen Affinity Purified
  • Gene: 654

Handling

  • Quantity: 25 µg
  • Storage: The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

Applications

  • Neutralization (Neut)
  • Western Blotting (WB)
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