DCS-156 reacts specifically with cdk4 protein present predominantly in G1 phase of cell cycle; it does not cross-react with cyclins. In immunohistochemical application on frozen sections of head and neck carcinoma (oropharynx and hypopharynx carcinoma) and cervix DCS-156 shows distinct nuclear staining, especially in tumor areas of enhanced proliferation. Epitope recognized: aa 270-290.
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Antigen: human recombinant full-length cdk4 polypeptide
- Clone: DCS-156
- Conjugate: unconjugated
- Isotype: IgG1
- Quantity: 50 µg
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- Immunohistochemistry (IHC)
- Western Blotting (WB)
