Argonaute 2 (Ago2, aka EIF2C2) is a member of the Argonaute family of proteins involved in RNAi mediated gene silencing through siRNA and miRNA effectors. The Argonaute proteins are part of RISC, the RNAi Induced Silencing Complex. Binding of RISC can inhibit mRNA translation and results in the degradation of the mRNA through the action of Ago2-mediated target cleavage.
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: 1B1-E2H5
- Isotype: IgG2a
- Quantity: 100 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Immunofluorescence (IF)
- Immunoprecipitation (IP)
- Western Blotting (WB)