ACK-1 (Activated CDC42 kinase 1) is a tyrosine kinase which mediates CDC42-dependent cell migration via phosphorylation of BCAR1. ACK-1 binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR. ACK-1 also participates in clathrin-mediated endocytosis.
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ACK-1.
- Isotype: Rabbit Ig
- Gene: Q07912
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)
