HLA DRA Antibody

5.0
/
5.0
  |  1 reviews


Product Details

Manufacturer
Cat. No.
NBP2-45043
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse

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Description

This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

Alternative Names

FLJ51114; histocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen DR alpha chain; HLA-DRA1; major histocompatibility complex class II DR alpha; MHC cell surface glycoprotein; MHC class II antigen DRA; MLRW

Biological Information

Clonality Monoclonal
Host Mouse
Reactivity Bovine, Cat (Feline), Human
Isotype IgG2b Kappa

Handling

Storage Store at 4°C.
Buffer 10mM PBS and 0.05% BSA

Applications

Flow Cytometry (FC), Immunocytochemistry (ICC), SDS-PAGE (SDS-PAGE)

Average Rating: 5.0
1 Scientist has reviewed this product

5 out of 5
Specificity
5 out of 5
Sensitivity
5 out of 5
Quality

Performs well.
Rating: 5.0

  • Application Area: Flow cytometry

  • Sample/Target/Tissue: Whole blood
"Antibody did what was intended. Was useful in showing MHCII+ cells in the sample."

Review date: 05 Sep 2018 | HLA DRA Antibody

Antibody Overview

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HLA DRA Antibody

5.0 / 5.0 | 1 reviews

Manufacturer:
Catalogue Number:
NBP2-45043
Antibody Type
Primary Antibody