HLA DRA Antibody
This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Product Details
- Cat. No.
- NBP2-45043
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
![Flow Cytometry: HLA DRA Antibody (169-1B5.2) [NBP2-45043] - A surface stain was performed on human peripheral blood lymphocytes with HLA DRA (169-1B5.2) antibody NBP2-47722APC and a matched isotype control NBP2-27231APC. Cells were incubated in an antibody dilution of 0.5 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-26646. Image using the Allophycocyanin form of this antibody.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/adc31ffd757230a30001a00f795c7421b72221d5-219x400.jpg?w=1080&q=75&fit=clip&auto=format)
Flow Cytometry: HLA DRA Antibody (169-1B5.2) [NBP2-45043] - A surface stain was performed on human peripheral blood lymphocytes with HLA DRA (169-1B5.2) antibody NBP2-47722APC and a matched isotype control NBP2-27231APC. Cells were incubated in an antibody dilution of 0.5 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-26646. Image using the Allophycocyanin form of this antibody.
![Flow Cytometry: HLA DRA Antibody (169-1B5.2) [NBP2-45043] - A surface stain was performed on human peripheral blood lymphocytes with HLA DRA (169-1B5.2) antibody NBP2-47722APC and a matched isotype control NBP2-27231APC. Cells were incubated in an antibody dilution of 0.5 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-26646. Image using the Allophycocyanin form of this antibody.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/adc31ffd757230a30001a00f795c7421b72221d5-219x400.jpg?w=256&q=75&fit=clip&auto=format)
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Reviews
Performs well.
Flow cytometry
Antibody did what was intended. Was useful in showing MHCII+ cells in the sample.
Review Date: 5 Sept 2018 | Novus Biologicals, LLC
Applications
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)
- SDS-PAGE (SDS-PAGE)
Antibody Overview
![Flow Cytometry: HLA DRA Antibody (169-1B5.2) [NBP2-45043] - A surface stain was performed on human peripheral blood lymphocytes with HLA DRA (169-1B5.2) antibody NBP2-47722APC and a matched isotype control NBP2-27231APC. Cells were incubated in an antibody dilution of 0.5 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-26646. Image using the Allophycocyanin form of this antibody.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/adc31ffd757230a30001a00f795c7421b72221d5-219x400.jpg?w=3840&q=75&fit=clip&auto=format)
About the company
Novus Biologicals, LLC
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research.
All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers