Scaling the potential of patient-derived organoids through automation and label-free image analysis of individual organoids
17 Mar 2023![Scaling the potential of patient-derived organoids through automation and label-free image analysis of individual organoids Scaling the potential of patient-derived organoids through automation and label-free image analysis of individual organoids](https://cdn.sanity.io/images/f5b6mtfn/selectscience-prod/564a277f1eabbd0ea552b21d92e3f34d9d1bc6c1-805x450.jpg?w=3840&q=75&fit=clip&auto=format)
3D patient-derived tumor organoids hold great potential for many basic and translational applications. However, traditional approaches to organoid image analysis and downstream data processing are often challenging and labor-intensive.
In this presentation, Dr. Christophe Deben, Group Leader of the University of Antwerp’s Tumoroid Screening Lab, demonstrates a semi-automated workflow for cell seeding drug treatment using the Tecan D300e digital drug dispenser and live-cell imaging using the Tecan Spark® Cyto* multimode plate reader. In addition, Deben illustrates the development and integration of label-free brightfield image analysis software (OrBITS) to monitor organoid growth rates and track movements.
This talk was presented, in partnership with Tecan, at SLAS2023.
*Spark® Cyto is for research use only. Not for use in diagnostic procedures.