Advancing analytical workflows for prohibited substance detection in equine athletes
18 Mar 2020

Despite advances in analytical chemistry, it is becoming increasingly challenging to control prohibited substance abuse in equine athletes. One such challenge is the ever-increasing number of prohibited substances, which require large custom-made compound databases and mass spectral libraries to allow for screening and testing.

In this webinar, Professor Scott Stanley and Dr. Sophie Bromilow from the Equine Analytical Research Laboratory will discuss the software tools available, how these can be implemented during method development, data acquisition, and data analysis, and how software compatibility across platforms enables the use of the Method Editor tool to ultimately advance analytical workflows.

Here, Stanley and Bromilow will outline the development of a >440 compound screen, with a custom-built mass spectral library and compound database, including the transfer of this method from a Thermo ScientificTM Orbitrap ExplorisTM 480 MS to a Thermo ScientificTM TSQ AltisTM mass spectrometer for confirmation. They will also demonstrate the integration of multiple software tools, including mzCloud, mzVault, and Thermo ScientificTM TraceFinderTM SW, for a holistic view of method development beyond analytical capabilities.

Learning objectives

  • Understand the analytical challenges of confidently detecting and identifying prohibited substances
  • Discover how integrated software tools can drive rapid method development from a discovery environment through to routine screening and confirmation
  • See how connected hardware platforms and software tools aid in method transfer and help to advance analytical workflows to combat the issues of prohibited substance detection
  • Better understand how a connected laboratory is now a reality and can help with small molecule compound identification and quantitation workflow deployment

Who should attend:

  • Researchers and leaders in academia, bio/pharma, clinical, forensic toxicology, and protein research, and any laboratories who are focused on both small molecule and protein identification and quantitation workflows where there is the need to transfer knowledge from research through to routine
  • Lab directors and industry experts who are responsible for setting new standards and, when needed, demonstrate success in challenging or high-profile work
  • Technology leaders responsible for the competitive edge while improving productivity and efficiency with highly trained operators
  • Principle scientists in screening and quantitative applications who need the best technology to advance their research discoveries and develop new testing methodologies

Thermo Fisher Scientific