Unlock complex cell-based binding and avidity dynamics

Feb 27, 2025 – 15:00 GMT / 16:00 CET / 10:00 EST / 7:00 PST

Join Dr. Nichole Cerutti, Director of Biophysics at RoukenBio, and Dr. Vivien Hafner, Head of Scientific Communication and Marketing at Bruker Biosensors to unlock the power within single-cell interaction cytometry, and its key role in the development of therapeutics.

These industry experts will showcase the innovative IndEx-2 system created to enable control of titratable protein expression levels. Learn how the combination of the IndEx-2 system and single-cell interaction cytometry can enhance the understanding of therapeutic interactions and efficacy at the cellular level, in the context of different levels of target protein expression.

Key learning objectives

• Understand how different levels of target expression can affect the key characteristics of targeted therapeutics with the IndEx-2 platform
• Discover single-cell interaction cytometry and how it can be used to characterize the kinetics of therapeutic molecules in a more physiologically relevant setting e.g. when binding to their targets on the cell surface
• Explore how the implementation of inducible cell lines with this technology can aid understanding of the binding capabilities of targeted therapeutics
• Learn how target density can influence the kinetics and avidity of molecule binding

Who should attend?

• Translational researchers working in drug discovery and development who are interested in biotherapeutic molecule development, particularly in the areas of oncology, immuno-oncology, auto-immunity, allergy and inflammatory diseases.

Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.