Transforming clinical trials with scalable immune monitoring approaches
Tuesday, November 11, at 15:00 GMT | 16:00 CET | 10:00 EST | 7:00 PST
The development of effective therapeutics relies on high-quality immune phenotyping data collected in clinical trials. Yet, traditional approaches to longitudinal immune monitoring are limited by complex logistics, strict sample-handling requirements and reagent stability issues. These factors can compromise data quality and limit access to geographically dispersed centers.
In this SelectScience® webinar, Helen McGuire, Ph.D., will present a simplified workflow for executing a large-scale immune monitoring strategy, built on a 50-plex lyophilized CyTOF™ assay. She will discuss how this approach enabled her team to expand the implementation of their novel proteomic immune signature of lung cancer non-responsiveness to remote settings, allowing access to underrepresented populations. This scalable workflow opens the door for broader site collection, transforming multi-site clinical studies with standardizing reagents to enable consistent and reproducible data across diverse trial centers.
This webinar will discuss:
- Immune monitoring for improved cancer prognosis: A novel immune signature that robustly predicts failure to make a clinical response to checkpoint therapies targeting the PD-1/PD-L1 pathway in melanoma and lung cancer
- Standardized immune monitoring with LyoMax™ CyTOF Panels: How dried-down antibody panels, enabled through Custom Lyophilization Service, reduce variability and streamline workflows. This workflow, unique to mass cytometry, enables large-scale immune monitoring while minimizing technical variation via sample barcoding and freezing of stained samples for shipment to a central site for batch acquisition.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
Webinar details
- Cost: Free to attend
- Location: Online
- Duration: 60 minutes
Registration is required to secure your place. If you register but cannot attend live, you will receive a link to the on‑demand recording once it becomes available.
Speakers
Who should attend?
- Clinical researchers
- Immunologists
- Laboratory directors
- Translational scientists
- Anyone involved in multi-site clinical trials or immune monitoring studies
What will this webinar cover?
Key learning objectives:
- Understand how a novel immune signature can predict clinical nonresponse to checkpoint inhibitors in cancer.
- Gain practical insights into implementing large-scale immune monitoring workflows with standardized, lyophilized CyTOF panels.
- Discover how to minimize technical variation and optimize multi-site sample acquisition for reliable, reproducible data.
Join the webinar to get answers to these questions:
- How can a novel immune signature predict nonresponse to PD-1/PD-L1 checkpoint inhibitors in melanoma and lung cancer?
- What are the key steps in a large-scale immune monitoring workflow using lyophilized CyTOF panels?
- How do LyoMax CyTOF Panels reduce variability and streamline multi-site clinical trial workflows?
- What strategies minimize technical variation in mass cytometry, including barcoding and frozen shipment?
- How can centralized batch acquisition improve data consistency across diverse clinical trial centers?