SelectScience InterviewsLife Sciences

Unmatched Accuracy for Nanoliter Dispensing

30 Apr 2010
Unmatched Accuracy for Nanoliter Dispensing

Learn more about the Echo 555 Acoustic Droplet Ejection system and the Echo 1536 low dead volume source plate from Labcyte. The Echo 555 provides non-contact liquid handling transfers from as many as 660,000 wells per day. The 1536 achieves 50% less dead volume with at least 15% higher throughput than its predecessor. SBS 2010 interview.

Echo® 555 Liquid Handler

Beckman Coulter Life Sciences

Echo® 555 liquid handler - the world's fastest acoustic dispensing platform for life science applications. The Echo® 555 liquid handler is the world’s fastest acoustic liquid handling platform for life science applications. Laboratories that demand very high throughput rely upon the Echo 555 liquid handler for round-the-clock trouble-free operation to enable the fastest discovery.The Echo 555 doubles the throughput of the Echo 550 and provides transfers from as many as 660,000 wells per day. Like the Echo 520 and Echo 550 liquid handlers, the Echo 555 uses "touchless" ADE transfer technology. ADE uses sound energy to transfer 2.5 nL droplets from Echo-qualified 384- and 1536-well source plates into 96-, 384-, 1536- and 3456-well destination plates.This unique touchless technology eliminates consumable tip costs, washing, and cross-contamination. Unsurpassed volumetric precision (≤ 8% CV) and accuracy (≤ 10% CV) ensure superior results. Independent studies have shown that Echo liquid handlers eliminate false negatives due to sample loss on tip surfaces in low-concentration transfers. Like the Echo 550 liquid handler, the Echo 555 liquid handler reports both fluid volume and DMSO hydration.Echo® 555 Liquid Handler Features: Tipless transfer, resulting in dramatic cost savings Accurate, precise movement of nanoliter-scale quantities, enabling assay miniaturization and further reducing costs Elimination of cross-contamination, carryover or leachates Better results through direct dilution of compounds, an improvement over serial dilution methods Improved information about sample integrity and improved transfer quality through measurement of DMSO hydration level Applications: Compound management Compound screening siRNA screening Biochemical assays Cell-based assays PCR Genotyping Gene expression

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Echo® Qualified 1536-Well High-Base Microplate

Echo®  qualified source plates are required for reliable dispensing with Echo® liquid handlers. These plates have been designed and tested for optimal performance in ADE and our software has been developed to ensure the reliable dispensing with these plates. Labcyte researchers have more than 100 years of combined experience in acoustic physics and have applied this unique and diverse knowledge to development of these source plates. 1536-Well High-Base COC (cyclic olefin copolymer) Source Microplate Clear, Flat Bottom Working range: 2-6 mL Catalogue number LP-03730 Bar-coded plates available.

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Unmatched Accuracy for Nanoliter Dispensing