Multiplex Screening of KRAS Mutations in Cell-Free DNA Colorectal Cancer Samples

This application note describes a ddPCR KRAS Screening Multiplex Kit for screening actionable KRAS mutations using DeopletDigital PCR (ddPCR). The ability to screen for multiple KRAS mutations down to 0.2% in a single well reduces the likelihood that mutations will be missed in poor-quality cell-free DNA anf formalin-fixed, paraffin-embedded (FFPE) samples with limited amounts of amplifiable DNA.