ResourceForensics

Analysis of xylazine, opioids, and other common adulterants in blood and urine by SPE and LC-MS/MS

19 Oct 2023

In this application note, UCT, Inc. outlines a method for simultaneously analyzing fentanyl, its analogs, xylazine, and other common adulterants using solid-phase extraction (SPE) and LC-MS/MS. Xylazine, a veterinary sedative, is increasingly used as an adulterant, particularly in fentanyl-containing substances. This combination, known as 'Tranq', poses serious risks, including unconsciousness and heightened addiction, potentially leading to fatal overdoses.

Select pH Buffer Pouches

UCT, Inc.

Select pH Buffer Pouches - UCT has developed a line of premeasured “ready-to-use” phosphate and acetate buffer pouches. These pouches contain the correct quantity of reagent to quickly and accurately prepare buffers at the correct pH and concentration to simplify solid-phase extraction methods.

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Clean Screen® DAU Solid Phase Extraction Columns

UCT, Inc.

Clean Screen® DAU Solid Phase Extraction Column is the flagship product of the forensic solid phase extraction column line. The first product of its kind in the industry, it is a mixed-mode column exhibiting both hydrophobic and cation exchange characteristics. Over 20 years of experience has shown this column to be effective on hundreds of drugs in both the acid-neutral and basic drug categories.

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Analysis of xylazine, opioids, and other common adulterants in blood and urine by SPE and LC-MS/MS