Drug discovery > Target Discovery Products & Reviews
Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
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THq
OMNI International Inc.The THQ is a digital homogenizer that can handle a wide range of samples from 0.20 mL to 120 mL. It provides reliable, repeatable performance with an ultra-quiet brushless motor. An integrated digital speed control stores the last set speed for ultimate repeatability. The THQ is compatible with Omni Tip™ disposable generator probes, stainless steel generator probes from 5 mm to 12 mm diameter and hybrid generator probes. The T…
Micro Hb
OMNI International Inc.The Micro Homogenizer is a hand-held battery powered rotor-stator homogenizer designed for use inside or outside of a laboratory setting. The Micro Homogenizer is powered by 12 volt lithium ion battery that provides operating speeds from 5,000 to 30,000 rpm for rapid homogenization of samples in volumes from 0.20 mL to 100 mL. It is an ideal solution for field based homogenization procedures involving the processing of tissues…
Vortex Mixer 24
OMNI International Inc.From vigorous vortexing to gentle mixing, the Vortex Mixer 24 is designed to conveniently handle samples for a variety of applications. The optional 2 ml Plus Tube Carriage (sold separately) is a unique, dual purpose tube carriage allows for vortexing tubes in the center of the device without having to remove the carriage.
UNISTAT®
SynbiosisStatistical analysis UNISTAT® bioassay analysis software has been integrated for use with ProtoCOL 3 colony counting and inhibition zone measuring system. The statistical module allows scientists a quick, easy method of analysing their ProtoCOL 3 data to generate accurate antibiotic and vaccine potency results. With just one click of the new UNITSTAT bioassay statistics module, microbiologists can export inhibition zone…
Teleshake 95 AC
INHECO GmbHHigh performance compact heater-shaker with secure fixing for variable plates
LUNARIS Human 11-Plex Cytokine Kit / 96
AYOXXA Biosystems GmbHMultiplex protein analysis in human serum and cell culture supernatant
LUNARIS Mouse 12-Plex Th17 Kit / 96
AYOXXA Biosystems GmbHMultiplex protein analysis in murine serum and cell culture supernatant
LUNARIS Mouse 12-Plex Cytokine Kit / 96
AYOXXA Biosystems GmbHMultiplex protein analysis in murine serum and cell culture supernatant
LUNARIS Mouse 12-Plex Cytokine Kit / 384
AYOXXA Biosystems GmbHMultiplex protein analysis in murine serum and cell culture supernatant
LUNARIS Mouse 12-Plex Th17 Kit / 96
AYOXXA Biosystems GmbHMultiplex protein analysis in murine serum and cell culture supernatant
LUNARIS Mouse 12-Plex Th17 Kit / 384
AYOXXA Biosystems GmbHMultiplex protein analysis in murine serum and cell culture supernatant
LUNARIS Human 6-Plex Ophthalmology Kit / 96
AYOXXA Biosystems GmbHMultiplex protein analysis in human aqueous humor, vitreous humor, tears
LUNARIS Human 6-Plex Ophthalmology Kit / 384
AYOXXA Biosystems GmbHMultiplex protein analysis in human aqueous humor, vitreous humor, tears
Invitrogen™ eBioscience™ JC-1 Mitochondrial Membrane Potential Dye
Thermo Fisher ScientificJC-1 is a membrane permeable dye widely used for determining mitochondrial membrane potential in flow cytometry and fluorescent microscopy. This dye can selectively enter the mitochondria where it reversibly changes coloras membrane potentials increase (over values of about 80-100 mV). When excited at 488 nm, the emission shift goes from 530 nm (monomeric JC-1) to 590 nm (aggregate JC-1), which are easily detected using filter…
Invitrogen™ eBioscience™ Calcium Sensor Dye eFluor™ 514
Thermo Fisher ScientificeFluor 514 Calcium Sensor Dye is a membrane-permeable dye used for monitoring changes in intracellular free calcium concentrations in the cell using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. When it enters a cell, cellular esterases cleave the dye, resulting in a membrane-impermeable dye that fluoresces at ~520 nm. eFluor™ 514 Calcium Sensor Dyeis a commonly used dy…
Invitrogen™ eBioscience™ DRAQ5™ Dye
Thermo Fisher ScientificDRAQ5, an anthraquinone dye with high affinity for double-stranded DNA, is a membrane-permeable dye that can label live or fixed/dead cells. The dye is used to distinguish nucleated and non-nucleated cells in flow cytometry, to report nuclear DNA content for ploidy and cell cycle analysis and as a nuclear counterstain nuclei in fluorescent microscopy.DRAQ5 can be excited by wavelengths from 488 to 647 nm. For microscopy/imagin…
Invitrogen™ eBioscience™ Cell Stimulation Cocktail (plus protein transport inhibitors) (500X)
Thermo Fisher ScientificThe Cell Stimulation Cocktail (plus protein transport inhibitors) (500X) is a cocktail of phorbol 12-myristate 13-acetate (PMA), ionomycin, brefeldin A and monensin. PMA and ionomycin treatment can induce activation of many cell types to produce cytokines. Brefeldin A and Monensin result in the accumulation of secreted proteins in the endoplasmic reticulum and Golgi apparatus. The Cell Stimulation Cocktail (plus protein transp…
Invitrogen™ eBioscience™ Phytohemagglutinin-L (PHA-L) Solution (500X)
Thermo Fisher ScientificThe Phytohemagglutinin-L (PHA-L) Solution (500X) is a ready-to-use solution of PHA-L in aqueous buffer. PHA is a mixture of lectins isolated from the red kidney bean, Phaseolus vulgaris. PHA-L is the fraction of PHA that exhibits strong leukoagglutinating and mitogenic activity, but very little erythroagglutinating activity. This reagent is intended for use in in vitro activation of human and mouse leukocytes.
Invitrogen™ eBioscience™ Concanavalin A (Con A) Solution (500X)
Thermo Fisher ScientificThe Concanavalin A (Con A) Solution (500X) is a ready-to-use solution of Con A in aqueous buffer. Con A, isolated from the Jack bean, Canavlia ensiformis, is a lectin that binds alpha-D-glucose and alpha-D-mannose moieties found in various glycoproteins, glycolipids, and sugars and is a potent leukocyte mitogen. This reagent is intended for use in in vitro activation of human and mouse leukocytes.
Invitrogen™ CellEvent™ Caspase 3/7 Green Ready Flow™ Reagent
Thermo Fisher ScientificCellEvent Caspase-3/7 Green Ready Flow Reagent enables the flow cytometric detection of activated caspase-3 and caspase-7 in apoptotic cells. The product includes 2 reagents: the novel fluorogenic substrate CellEvent Caspase-3/7 Green Detection Reagent and SYTOX™ AADvanced™ Dead Cell Stain.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteExceptionally bright green fluorescen…
Invitrogen™ Click-iT™ EdU Alexa Fluor™ 647 Flow Cytometry Assay Kit
Thermo Fisher ScientificThe Click-iT EdU Alexa Fluor 647 Flow Cytometry Assay Kit provides a simplified, more robust assay for analyzing DNA replication in proliferating cells as compared to traditional BrdU methods. The Click-iT EdU Flow Cytometry Assay Kits rely on EdU (5-ethynyl-2´-deoxyuridine), a thymidine analog which is incorporated into DNA during active DNA synthesis, which is then detected using click chemistry, a copper catalyzed covalent…
Invitrogen™ Click-iT™ EdU Alexa Fluor™ 488 Flow Cytometry Assay Kit
Thermo Fisher ScientificThe Click-iT EdU Alexa Fluor 488 Flow Cytometry Assay Kit provides a simplified, more robust assay for analyzing DNA replication in proliferating cells as compared to traditional BrdU methods. The Click-iT EdU Flow Cytometry Assay Kits rely on EdU (5-ethynyl-2´-deoxyuridine), a thymidine analog which is incorporated into DNA during active DNA synthesis, which is then detected using click chemistry, a copper catalyzed covalent…