Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Flare™

Cresset

Flare™ is a ligand-based and structure-based drug design platform. Through high-resolution 3D visualization and in-depth analysis of target structures and potential ligands, Flare enables users to optimize and prioritize new molecules efficiently and effectively.

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Flare™ Visualizer

Cresset

Flare™ enables the production of high-resolution 3D graphics of your ligands and proteins for publications and communication of results.

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Flare™ FEP

Cresset

Flare™ FEP enables research chemists to refine docking results, making the right structure-based design choices for lead optimization with confidence.

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Spark™

Cresset

Spark™ is a powerful scaffold hopping and bioisosteric replacement solution that generates highly innovative ideas for your project to explore chemical space and escape IP and toxicity traps.

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Blaze™

Cresset

Blaze™ is an advanced virtual screening platform enabling you to dramatically increase your wet screening hit rate at a fraction of the cost.

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Discovery CRO

Cresset

Cresset Discovery is a premier computational chemistry CRO with a proven track record delivering high impact drug discovery projects. From ideation to synthesis and biological results, their expert CADD scientists are the best at what they do. Working alongside you from the ground up, they apply the best in silico techniques, and give expert advice and guidance, to accelerate your assets through the pipeline.

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Cyto-Surf® A

Sphere Bio

Cyto-Surf® A is required to operate Cyto-Mine®. It provides the oil phase of our water-in-oil picodroplet system and is fully optimized for use with Cyto-Mine®.

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Cyto-Surf® B

Sphere Bio

Cyto-Surf® B is required to operate Cyto-Mine®. It provides the surfactant necessary to make stable biocompatible picodroplets and is fully optimized for Cyto-Mine®.

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Cyto-Cartridges®

Sphere Bio

Cyto-Cartridge® provides the core microfluidic functions used by Cyto-Mine® to implement picodroplet workflows. It is a single-use, fully disposable device to ensure zero cross-contamination between runs and maintain cell quality.

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AmMag™ Quatro Automated Maxi-Scale Plasmid Purification System

GenScript

AmMag™ Quatro is an automated solution for purification of maxi-scale, high-quality, transfection-grade plasmids. The comprehensive solution consists of a system controller that provides simultaneous operation of up to 4 independent purification modules, along with pre-filled consumables and verified protocols. Each purification module can process up to 6 samples in one run.

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GenScript LNP Solutions: Ready-Edit and Targeted LNP services

GenScript

GenScript’s Ready-Edit and Targeted LNP services enable precise gene editing and targeted RNA delivery for advanced therapeutics. Ready-Edit LNPs co-encapsulate CRISPR components for efficient gene modifications, while Targeted LNPs use customizable ligands for accurate payload delivery. Maximize efficacy, minimize off-target effects, and accelerate your research with GenScript’s cutting-edge solutions.

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