SHR Rat by Charles River Laboratories
Okamoto, Kyoto School of Medicine, 1963, from outbred Wistar Kyoto male with marked elevation of blood pressure mated to female with slightly elevated blood pressure.
Brother x sister mating with continued selection for spontaneous hypertension was then started. To NIH in 1966 from Okamoto at F13. To Charles River from NIH in 1973 at F32.Model Properties:
Coat Color: White (albino)
MHC Haplotype: RT1k
Ideal For: genetic hypertension, hypertensive drug research, ADHD model, safety and ef... Read more