Okamoto, Kyoto School of Medicine, 1963, from outbred Wistar Kyoto male with marked elevation of blood pressure mated to female with slightly elevated blood pressure.
Brother x sister mating with continued selection for spontaneous hypertension was then started. To NIH in 1966 from Okamoto at F13. To Charles River from NIH in 1973 at F32.Model Properties:
Coat Color: White (albino)
MHC Haplotype: RT1k
Ideal For: genetic hypertension, hypertensive drug research, ADHD model, safety and ef... Read more