NEBNext® Enzymatic Methyl-seq Conversion Module by New England Biolabs Inc.

4.7
/
5.0
  |  1 reviews
NEBNext® Enzymatic Methyl-seq (EM-seq™) is a new method for identification of 5-mC and 5-hmC.


NEBNext® Enzymatic Methyl-seq Conversion Module by New England Biolabs Inc. product image
NEBNext® Enzymatic Methyl-seq Conversion Module

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Average Rating: 4.7
1 Scientist has reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money


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    Advanced Reviewer
  • Member since: 2021

  • Organization: St jude childrens research hospital



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Uniform and easy protocol.
Rating: 4.7

  • Application Area: Epigenetic methylation analyses

"The NEBNext EMseq kit is a very good alternate to bisulfite sequencing to analyze the CpG methylated sites. I have been using this kit for mouse genomics DNA for methylation analyses. It's very simple and highly efficient compared to conventional bisulfite sequencing from our hand."

Review date: 07 Jun 2021 | NEBNext® Enzymatic Methyl-seq Conversion Module

While bisulfite sequencing has been the gold standard for methylome analysis, this conversion treatment damages DNA, resulting in fragmentation, loss and bias. The NEBNext Enzymatic Methyl-seq Conversion Module provides an enzyme-based alternative to bisulfite conversion.

For use in Illumina® sequencing workflows, they recommend use of the NEBNext Enzymatic Methyl-seq Kit (NEB #E7120) instead of this module. The full kit includes the EM-seq Adaptor, which has been optimized for high performance in the EM-seq workflow, as well as the high-efficiency Ultra II library prep reagents, and these components are not included in the Conversion Module.

  • High efficiency conversion
  • Minimal DNA damage
  • Minimized GC bias
  • 5-mC and 5-hmC detection
  • Complete kit including library prep reagents also available

Product Overview

NEBNext® Enzymatic Methyl-seq Conversion Module by New England Biolabs Inc. product image

NEBNext® Enzymatic Methyl-seq Conversion Module

Manufacturer New England Biolabs Inc.

4.7 / 5.0 | 1 reviews