Microsatellite Instability Analysis (MSI) by Promega Corp.

Manufacturer Promega Corp.
4.5
/
5.0
  |  2 reviews
Characterize MSI Status of Your Research Samples


Microsatellite Instability Analysis (MSI) by Promega Corp. product image
Microsatellite Instability Analysis (MSI)
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Average Rating: 4.5
2 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2019

  • Organization: Circulogene



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Great service.
Rating: 4.3

  • Application Area: Analyze mismatch repair

"Great value for the money. Great results. Great turn around time after ordering."

Review date: 25 Oct 2019 | Microsatellite Instability Analysis (MSI)
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: FALCO biosystems Ltd.



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great throughput of MSI test for CDx diagnosis.
Rating: 4.7

  • Application Area:Detect MSI-High for administration of Keytruda

"We used Bethesda panel for a test of MSI of the diagnosis of Lynch's syndrome before, but it requires many steps (5 tubes for 1 sample). But we are able to test MSI with 1 tube by Promega's product ."

Review date: 05 Jul 2018 | Microsatellite Instability Analysis (MSI)

Focus Your Research on DNA Mismatch Repair Dysfunction Using the Proven Gold Standard Method

The MSI Analysis System, Version 1.2, is a fluorescent multiplex PCR-based method for detecting microsatellite instability (MSI). MSI is a form of genomic instability caused by the insertion or deletion of repeating bases called microsatellites during DNA replication and the failure of the mismatch repair system (MMR) to correct these errors

Characterizing MSI Status

MSI analysis typically involves comparing allelic profiles of microsatellite markers generated by amplification from matching pairs of test samples. The presence of alleles in the abnormal sample that are not found in the corresponding normal sample are indicative of MSI. The Promega MSI Analysis System includes seven multiplexed  markers for analysis of the MSI-high (MSI-H) phenotype; five nearly monomorphic mononucleotide repeat markers (BAT-25, BAT-26, MONO-27, NR-21 and NR-24) and two highly polymorphic pentanucleotide repeat markers (Penta C and Penta D) , which are a quality control for sample authentication of matched normal and tumor. 

Product Overview

Microsatellite Instability Analysis (MSI) by Promega Corp. product image

Microsatellite Instability Analysis (MSI)

Manufacturer Promega Corp.

4.5 / 5.0 | 2 reviews